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Expected Impact
TLR ligands as alternate targets - Various TLR ligands could serve as alternate targets for increasing the potency of existing vaccines and for therapeutic intervention.

Breeding for disease resistance – The identified SNPs responsible for increased TLR gene expression can be exploited in marker based selection programmes.

Disease Resistance Chip - Using this microarray based method to quantify TLR and cytokine mRNA, other breeds of buffalo and goat can be screened for disease resistance potential.